Humankind is the best art of God on Earth. Islam gives a great importance for all human beings regardless of their ethnic, cultural and religious back round. In the Quran it is stated that saving one human being is like saving all humankind and killing one is like killing all. Accordingly, through organ donation saving a person is permissible in Islam as long as the body of donor is not abused or not treated disrespectfully. Because, the body of human being whether alive or dead cannot be tortured or be treated as spare parts. There must be bioethics and strict regulations in order to avoid abuses, mistreatment and misusage of the body of the donor. It is not permissible to sell organs or take the organs from the dead without the consent of the legal guardians. Hospitals or the institutions which transfer organs from person to person must act with great caution so they do not violate the dignity and honor of the human body. The funeral service and funeral prayer in Islam indicate that human body deserves best treatment. Whatever which contradicts the human honor is not permissible in Islam. In short, organ donation is permissible in Islam, even it can be regarded as good deed with the condition that the body of dead is not treated disrespectfully or deemed as spare parts.